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KMID : 1191520060110010001
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Journal of Korean Traditional Oncology
2006 Volume.11 No. 1 p.1 ~ p.21
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The Study on the Safety and Case Series of the Acute Lymphocytic Leukemia using Rhus Verniciflua Stokes Extract (Nexia)
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Park Jae-Woo
Kim Kyung-Suk
Jung Hyun-Sik
Choi Won-Cheol
Yoon Seoung-Woo
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Abstract
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This study was undertaken to evaluate safety and antitumor activity of Nexia, a processed extract of Rhus verniciflua STOKES by heating according to Korean patent 0504160 through toxicology, cancer research and clinical application. Nexia did not exhibit any toxicological symptoms through 13 week continuous treatment, dosage accumulation study and anaphylaxis response. The lifespan of four patients with acute lymphocytic leukemia under complete remission were 110, 83, 97, and 86 months after treatment of Nexia, respectively. These data suggest that Nexia, a processed extract by removing allergen from Rhus verniciflua STOKES, may have safety and antitumor activity and also still need continuous study on its mechanism and clinical trial.
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KEYWORD
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Rhus Verniciflua Stokes(Nexia) , safety , acute lymphocytic leukemia
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